Pdpk1^tm1Jcbr
Targeted Allele Detail

Summary

• Symbol: Pdpk1^tm1Jcbr
• Name: 3-phosphoinositide dependent protein kinase 1; targeted mutation 1, Jens C Bruning
• MGI ID: MGI:3790718
• Synonyms: PDK1^fldeltaneo
• Gene: Pdpk1 Location: Chr17:24292654-24369898 bp, - strand Genetic Position: Chr17, 12.23 cM, cytoband A3.3
• Alliance: Pdpk1^tm1Jcbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134336
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• No details given. (J:134336)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdpk1 Mutation: 138 strains or lines available

References

• Original: J:134336 Belgardt BF, et al., PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response. Cell Metab. 2008 Apr;7(4):291-301
• All: 2 reference(s)