Foxd3^tm3Lby
Targeted Allele Detail

Summary

• Symbol: Foxd3^tm3Lby
• Name: forkhead box D3; targeted mutation 3, Patricia A Labosky
• MGI ID: MGI:3790794
• Synonyms: Foxd3^fl, Foxd3^flox
• Gene: Foxd3 Location: Chr4:99544536-99546859 bp, + strand Genetic Position: Chr4, 45.71 cM
• Alliance: Foxd3^tm3Lby page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134482
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted downstream of the coding region and an additional loxP site was inserted upstream of the coding region. (J:134482)

Expression

In Structures Affected by this Mutation:

19 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxd3 Mutation: 10 strains or lines available

References

• Original: J:134482 Teng L, et al., Requirement for Foxd3 in the maintenance of neural crest progenitors. Development. 2008 May;135(9):1615-24
• All: 14 reference(s)