Tg(Myh6-TNNT2)3Jdp
Transgene Detail

Summary

• Symbol: Tg(Myh6-TNNT2)3Jdp
• Name: transgene insertion 3, James D Potter
• MGI ID: MGI:3793475
• Synonyms: HCTnT, Tg-WT
• Transgene: Tg(Myh6-TNNT2)3Jdp Location: unknown
• Alliance: Tg(Myh6-TNNT2)3Jdp page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-TNNT2)3Jdp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNNT2 (7139)

  Tnnt2

  (MGI:104597)

• Mutation details: The transgene construct consists of about 5.5 kilobases of the mouse alpha-myosin heavy chain promoter, including the first 2 exons and part of the third, followed by the human TNNT2 cDNA (876 base pairs), and a 630-base pair 3'-untranslated region from the human growth hormone transcript. (J:67284)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:67284 Miller T, et al., Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation. J Biol Chem. 2001 Feb 9;276(6):3743-55
• All: 8 reference(s)