Celsr3^tm2Agof
Targeted Allele Detail

Summary

• Symbol: Celsr3^tm2Agof
• Name: cadherin, EGF LAG seven-pass G-type receptor 3; targeted mutation 2, Andre M Goffinet
• MGI ID: MGI:3793629
• Synonyms: Celsr3^f
• Gene: Celsr3 Location: Chr9:108703519-108730168 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Celsr3^tm2Agof page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98367
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted downstream of exon 27 and an additional loxP site was inserted downstram of exon 18. (J:98367)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celsr3 Mutation: 122 strains or lines available

References

• Original: J:98367 Tissir F, et al., Protocadherin Celsr3 is crucial in axonal tract development. Nat Neurosci. 2005 Apr;8(4):451-7
• All: 21 reference(s)