Tg(Osr1-cre)4Mrt
Transgene Detail

Summary

• Symbol: Tg(Osr1-cre)4Mrt
• Name: transgene insertion 4, Gail R Martin
• MGI ID: MGI:3793846
• Synonyms: Osr1-Cre
• Transgene: Tg(Osr1-cre)4Mrt Location: unknown
• Alliance: Tg(Osr1-cre)4Mrt page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Osr1-cre)4Mrt expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Osr1 (MGI:1344424)

• Mutation details: A mouse Osr1 promoter was used to drive expression of a cre gene with a nuclear localization signal followed by an IRES-EGFP in enodermal organs including the posterior foregut, midgut, hindgut and developing urogeital system, heart left atrium, limb mesenchyme, and extra-ocular muscle. Two founder lines were established with line 4 chosen as the representative line. (J:135303)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Osr1 (mouse) Summary of all recombinase alleles driven by Osr1. Comparative matrix view of recombinase activities Alliance mouse Osr1 gene page

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(Osr1-cre)4Mrt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:135303 Grieshammer U, et al., A Cre transgene active in developing endodermal organs, heart, limb, and extra-ocular muscle. Genesis. 2008 Feb;46(2):69-73
• All: 11 reference(s)