Sfrp5^tm1Aksh
Targeted Allele Detail

Summary

• Symbol: Sfrp5^tm1Aksh
• Name: secreted frizzled-related sequence protein 5; targeted mutation 1, Akihiko Shimono
• MGI ID: MGI:3793862
• Gene: Sfrp5 Location: Chr19:42186410-42190691 bp, - strand Genetic Position: Chr19, 35.93 cM, cytoband D1
• Alliance: Sfrp5^tm1Aksh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135313
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The 5' coding region in the first exon encoding the cystein rich domain was replaced with a neo cassette followed by and IRES-YFP variant with multiple stop codons. (J:135313)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp5 Mutation: 27 strains or lines available

References

• Original: J:135313 Satoh W, et al., Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis. 2008 Feb;46(2):92-103
• All: 7 reference(s)