Abca4^tm1Kpal
Targeted Allele Detail

Summary

• Symbol: Abca4^tm1Kpal
• Name: ATP-binding cassette, sub-family A member 4; targeted mutation 1, Krzysztof Palczewski
• MGI ID: MGI:3793964
• Synonyms: Abca4^-
• Gene: Abca4 Location: Chr3:121838092-121973772 bp, + strand Genetic Position: Chr3, 52.94 cM
• Alliance: Abca4^tm1Kpal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135257
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced with a neo cassette. (J:135257)

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abca4 Mutation: 108 strains or lines available

References

• Original: J:135257 Golczak M, et al., Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. J Biol Chem. 2008 Apr 11;283(15):9543-54
• All: 10 reference(s)