Tg(Cdh16-cre/ERT2)24Igr
Transgene Detail

Summary

• Symbol: Tg(Cdh16-cre/ERT2)24Igr
• Name: transgene insertion 24, Peter Igarashi
• MGI ID: MGI:3794556
• Synonyms: Ksp/CreER^T2, Tg(Cdh16-cre/ESR1)24Igr
• Transgene: Tg(Cdh16-cre/ERT2)24Igr Location: unknown
• Alliance: Tg(Cdh16-cre/ERT2)24Igr page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Cdh16-cre/ERT2)24Igr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Cdh16

• Mutation details: The Ksp-cadherin (Cdh16) promoter was used to drive the expression of a cre/ERT2 gene fusion in adult tubular epithelial cells in the kidney. Several lines were created (not specified) with line 24 with robust expression and no leakiness was chosen for further study. (J:135523)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdh16 (species not specified) Summary of all recombinase alleles driven by Cdh16. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:135523 Patel V, et al., Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet. 2008 Jun 1;17(11):1578-90
• All: 6 reference(s)