Cldn15^tm1Sats
Targeted Allele Detail

Summary

• Symbol: Cldn15^tm1Sats
• Name: claudin 15; targeted mutation 1, Sachiko Tsukita
• MGI ID: MGI:3794894
• Gene: Cldn15 Location: Chr5:136996723-137004699 bp, + strand Genetic Position: Chr5, 76.07 cM
• Alliance: Cldn15^tm1Sats page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135596
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on duodenum, jejunum, ileum and colon extracts. (J:135596)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cldn15 Mutation: 18 strains or lines available

References

• Original: J:135596 Tamura A, et al., Megaintestine in claudin-15-deficient mice. Gastroenterology. 2008 Feb;134(2):523-34
• All: 6 reference(s)