Ddx20^tm1Yosa
Targeted Allele Detail

Summary

• Symbol: Ddx20^tm1Yosa
• Name: DEAD box helicase 20; targeted mutation 1, Yoel Sadovsky
• MGI ID: MGI:3795148
• Synonyms: Dp103^-
• Gene: Ddx20 Location: Chr3:105585586-105594890 bp, - strand Genetic Position: Chr3, 46.43 cM, cytoband F3
• Alliance: Ddx20^tm1Yosa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136021
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 and all of intron 1 were replaced with a myc-tagged EGFP followed by a floxed neo cassette. The absence of protein product was confirmed by immunohistochemistry. This is a null allele and a reporter allele. (J:136021)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx20 Mutation: 33 strains or lines available

References

• Original: J:136021 Mouillet JF, et al., DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function. Endocrinology. 2008 May;149(5):2168-75
• All: 1 reference(s)