Brwd1^{Gt(AW0417)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Brwd1^{Gt(AW0417)Wtsi}
• Name: bromodomain and WD repeat domain containing 1; gene trap AW0417, Wellcome Trust Sanger Institute
• MGI ID: MGI:3795157
• Synonyms: Brwd1^Gt
• Gene: Brwd1 Location: Chr16:95793292-95883726 bp, - strand Genetic Position: Chr16, 56.77 cM
• Alliance: Brwd1^{Gt(AW0417)Wtsi} page

Mutation origin

• Mutant Cell Line: AW0417
• Germline Transmission: Earliest citation of germline transmission: J:136078
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• The gene trap vector pGT0lxr was inserted downstream of exon 34. (J:136078)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AW0417	CW989977 ; (MGI Seq Detail)	5' RACE	Chr16:95820618-95821070 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  48 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brwd1 Mutation: 106 strains or lines available

References

• Original: J:136078 Philipps DL, et al., The dual bromodomain and WD repeat-containing mouse protein BRWD1 is required for normal spermiogenesis and the oocyte-embryo transition. Dev Biol. 2008 May 1;317(1):72-82
• All: 1 reference(s)