Tsc2^tm1.1Kido
Targeted Allele Detail

Summary

• Symbol: Tsc2^tm1.1Kido
• Name: TSC complex subunit 2; targeted mutation 1.1, Yoshiaki Kido
• MGI ID: MGI:3795271
• Gene: Tsc2 Location: Chr17:24814790-24851604 bp, - strand Genetic Position: Chr17, 12.41 cM
• Alliance: Tsc2^tm1.1Kido page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135811
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Germ line, cre mediated recombination was used to remove exons 3 and 4. (J:135811)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsc2 Mutation: 78 strains or lines available

References

• Original: J:135811 Shigeyama Y, et al., Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice. Mol Cell Biol. 2008 May;28(9):2971-9
• All: 1 reference(s)