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Nmur1tm1Lex
Targeted Allele Detail
Summary
Symbol: Nmur1tm1Lex
Name: neuromedin U receptor 1; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3795273
Gene: Nmur1  Location: Chr1:86313964-86317083 bp, - strand  Genetic Position: Chr1, 43.94 cM, cytoband C5
Alliance: Nmur1tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135815
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsNucleotides 4117 to 4868 were replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on uterus and fundus extracts. (J:135815)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmur1 Mutation:  22 strains or lines available
References
Original:  J:135815 Prendergast CE, et al., Species-dependent smooth muscle contraction to Neuromedin U and determination of the receptor subtypes mediating contraction using NMU1 receptor knockout mice. Br J Pharmacol. 2006 Apr;147(8):886-96
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory