Dmp1^tm1.1Mis
Targeted Allele Detail

Summary

• Symbol: Dmp1^tm1.1Mis
• Name: dentin matrix protein 1; targeted mutation 1.1, Yuji Mishina
• MGI ID: MGI:3795591
• Synonyms: Dmp1^deltaE
• Gene: Dmp1 Location: Chr5:104350479-104361968 bp, + strand Genetic Position: Chr5, 50.61 cM
• Alliance: Dmp1^tm1.1Mis page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135314
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 6 was removed by germ line, cre-mediated recombination. The absence of protein product was confirmed by immunohistochemistry. (J:135314)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmp1 Mutation: 42 strains or lines available

References

• Original: J:135314 Feng JQ, et al., Generation of a conditional null allele for Dmp1 in mouse. Genesis. 2008 Feb;46(2):87-91
• All: 3 reference(s)