Msx2^tm1Yvla
Targeted Allele Detail

Summary

• Symbol: Msx2^tm1Yvla
• Name: msh homeobox 2; targeted mutation 1, Yvan Lallemand
• MGI ID: MGI:3795774
• Synonyms: Msx2^flox, Msx2^Flox-GFP
• Gene: Msx2 Location: Chr13:53620917-53626816 bp, - strand Genetic Position: Chr13, 27.84 cM
• Alliance: Msx2^tm1Yvla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136241
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into exon 1 upstream of the initiation codon, and an frt-flanked neomycin resistance cassette with a 3' loxP site, followed by an internal ribosomal entry site (IRES) and the coding sequence for green fluorescent protein (GFP), was inserted into the second exon downstream of the stop codon. The neo cassette was removed by germ line, flp-mediated recombination. This is a conditional knockout (floxed) allele and a reporter allele. (J:136241)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Msx2 Mutation: 23 strains or lines available

References

• Original: J:136241 Bensoussan V, et al., Generation of an Msx2-GFP conditional null allele. Genesis. 2008 May;46(5):276-82
• All: 7 reference(s)