Patz1^tm1Pchi
Targeted Allele Detail

Summary

• Symbol: Patz1^tm1Pchi
• Name: POZ (BTB) and AT hook containing zinc finger 1; targeted mutation 1, Paolo Chieffi
• MGI ID: MGI:3795851
• Gene: Patz1 Location: Chr11:3239131-3259083 bp, + strand Genetic Position: Chr11, 2.3 cM
• Alliance: Patz1^tm1Pchi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:133515
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: A neomycin selection cassette replaced a 2317-bp PstI-XhoI genomic fragment, including the start codon, the coding regions for the POZ domain, the AT-hook, and the first four zinc fingers. (J:133515, J:185619)

Expression

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Patz1^tm1Pchi

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Patz1 Mutation: 55 strains or lines available

References

• Original: J:133515 Fedele M, et al., PATZ1 gene has a critical role in the spermatogenesis and testicular tumours. J Pathol. 2008 May;215(1):39-47
• All: 4 reference(s)