Ssh3^tm1Taue
Targeted Allele Detail

Summary

• Symbol: Ssh3^tm1Taue
• Name: slingshot protein phosphatase 3; targeted mutation 1, Tadashi Uemura
• MGI ID: MGI:3796064
• Gene: Ssh3 Location: Chr19:4311696-4319208 bp, - strand Genetic Position: Chr19, 3.96 cM
• Alliance: Ssh3^tm1Taue page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136245
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 downstream of the initiation codon and exon 2 were replaced with a lacZ and neo cassette. The absence of protein product was confirmed by western blot analysis on kidney extracts. This is a null allele and a reporter allele. (J:136245)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ssh3 Mutation: 25 strains or lines available

References

• Original: J:136245 Kousaka K, et al., Slingshot-3 dephosphorylates ADF/cofilin but is dispensable for mouse development. Genesis. 2008 May;46(5):246-55
• All: 1 reference(s)