Akirin2^tm1.1Aki
Targeted Allele Detail

Summary

• Symbol: Akirin2^tm1.1Aki
• Name: akirin 2; targeted mutation 1.1, Shizuo Akira
• MGI ID: MGI:3796163
• Gene: Akirin2 Location: Chr4:34550937-34566908 bp, + strand Genetic Position: Chr4, 16.8 cM
• Alliance: Akirin2^tm1.1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130487
• Parent Cell Line: GSI-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ line, cre-mediated recombination was used to remove exon 1. The absence of transcript was confirmed by RT-PCR analysis. (J:130487)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akirin2 Mutation: 23 strains or lines available

References

• Original: J:130487 Goto A, et al., Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Nat Immunol. 2008 Jan;9(1):97-104
• All: 1 reference(s)