Actb^tm1Dost
Targeted Allele Detail

Summary

• Symbol: Actb^tm1Dost
• Name: actin, beta; targeted mutation 1, Douglas Strathdee
• MGI ID: MGI:3796617
• Synonyms: Actb^m1
• Gene: Actb Location: Chr5:142888870-142892509 bp, - strand Genetic Position: Chr5, 81.8 cM
• Alliance: Actb^tm1Dost page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136574
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• An IRES-betageo cassette was inserted into the 3'UTR 55 bp downstream of the translation stop codon. (J:136574)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Actb Mutation: 53 strains or lines available

References

• Original: J:136574 Strathdee D, et al., Distal transgene insertion affects CpG island maintenance during differentiation. J Biol Chem. 2008 Apr 25;283(17):11509-15
• All: 1 reference(s)