Cplx3^tm1Bros
Targeted Allele Detail

Summary

• Symbol: Cplx3^tm1Bros
• Name: complexin 3; targeted mutation 1, Nils Brose
• MGI ID: MGI:3796622
• Synonyms: Cplx3^tm1Rmnd
• Gene: Cplx3 Location: Chr9:57507275-57513564 bp, - strand Genetic Position: Chr9, 31.11 cM
• Alliance: Cplx3^tm1Bros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136393
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first coding exon was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on brain extracts. (J:136393)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cplx3 Mutation: 9 strains or lines available

References

• Original: J:136393 Xue M, et al., Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7875-80
• All: 12 reference(s)