Adgrg1^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Adgrg1^tm1Lex
• Name: adhesion G protein-coupled receptor G1; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3796624
• Synonyms: Gpr56-KO
• Gene: Adgrg1 Location: Chr8:95701379-95740845 bp, + strand Genetic Position: Chr8, 47.12 cM
• Alliance: Adgrg1^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136385
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a lacZ/neo cassette. The absence of protein product was confirmed by western blot anlaysis on brain extracts. This is a null allele and a reporter allele. (J:136385)

Expression

In Mice Carrying this Mutation:	35 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Adgrg1 Mutation: 33 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:136385 Li S, et al., GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26
• All: 18 reference(s)