Cdx4^tm1.1Gqda
Targeted Allele Detail

Summary

• Symbol: Cdx4^tm1.1Gqda
• Name: caudal type homeobox 4; targeted mutation 1.1, George Q Daley
• MGI ID: MGI:3796742
• Synonyms: Cdx4^GFP
• Gene: Cdx4 Location: ChrX:102365004-102373830 bp, + strand Genetic Position: ChrX, 46.06 cM
• Alliance: Cdx4^tm1.1Gqda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136405
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding exon was replaced with a GFP gene and a floxed and frt-flanked hygro-GFP cassette. Recombination in ES cells was used to remove the hygro cassette. This is a null allele and a reporter allele. (J:136405)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdx4 Mutation: 2 strains or lines available

References

• Original: J:136405 Wang Y, et al., Cdx gene deficiency compromises embryonic hematopoiesis in the mouse. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7756-61
• All: 1 reference(s)