Gt(ROSA)26Sor^{tm1(Trpv1,ECFP)Mde}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Trpv1,ECFP)Mde}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Michael D Ehlers
• MGI ID: MGI:3796847
• Synonyms: Rosa26^Trpv1, ROSA-stop flox-TRPV1-IRES-ECFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Trpv1,ECFP)Mde} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136582
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Trpv1,ECFP)Mde} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Trpv1 (83810)

  Trpv1

  (MGI:1341787)

• Mutation details: A targeting vector was used to insert a loxP-flanked neomycin cassette, rat Trpv1 (transient receptor potential cation channel, subfamily V, member 1) cDNA, and IRES-ECFP sequence into the Gt(ROSA)26Sor locus. (J:136582)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:136582 Arenkiel BR, et al., Genetic control of neuronal activity in mice conditionally expressing TRPV1. Nat Methods. 2008 Apr;5(4):299-302
• All: 16 reference(s)