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Rr148tm2Anbo
Targeted Allele Detail
Summary
Symbol: Rr148tm2Anbo
Name: regulatory region 148; targeted mutation 2, Andrea Bottaro
MGI ID: MGI:3796984
Synonyms: Ightm2Anbo, SV40eR
Gene: Rr148  Location: Chr12:113391013-113391258 bp  Genetic Position: Chr12, Syntenic
Alliance: Rr148tm2Anbo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136307
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  (129/Sv x C57BL/6)F1
Mutation
description
Allele Type:    Targeted (Modified regulatory region)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe Emu enhancer element was replaced with an SV40eR (SV40 enhancer region) and floxed neo cassette. Germ line, cre-mediated recombination was used to remove the neo cassette. (J:136307)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr148 Mutation:  0 strains or lines available
Notes
ES cell line = F1.11
References
Original:  J:136307 Kuzin II, et al., Requirement for enhancer specificity in immunoglobulin heavy chain locus regulation. J Immunol. 2008 Jun 1;180(11):7443-50
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory