Mgam^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Mgam^tm1Lex
• Name: maltase-glucoamylase; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3797062
• Gene: Mgam Location: Chr6:40605765-40746057 bp, + strand Genetic Position: Chr6, 18.82 cM
• Alliance: Mgam^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136590
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was partially replaced with a lacZ/neo cassette. The absence of protein product was confirmed by western blot analysis on jejunum extracts. This is a reporter allele and a null allele. (J:136590)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mgam Mutation: 96 strains or lines available

References

• Original: J:136590 Quezada-Calvillo R, et al., Contribution of mucosal maltase-glucoamylase activities to mouse small intestinal starch alpha-glucogenesis. J Nutr. 2007 Jul;137(7):1725-33
• All: 2 reference(s)