Zfp42^tm1Hini
Targeted Allele Detail

Summary

• Symbol: Zfp42^tm1Hini
• Name: zinc finger protein 42; targeted mutation 1, Hitoshi Niwa
• MGI ID: MGI:3797379
• Synonyms: Rex1^-
• Gene: Zfp42 Location: Chr8:43748100-43760017 bp, - strand Genetic Position: Chr8, 23.89 cM
• Alliance: Zfp42^tm1Hini page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136675
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 4 including the translation inititation site and 100 bp of coding sequence was replaced with a floxed pac-EGFP cassette. The absence of transcript was confirmed by quantitative RT-PCR. This is a null allele and a reporter allele. (J:136675)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp42 Mutation: 44 strains or lines available

References

• Original: J:136675 Masui S, et al., Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells. BMC Dev Biol. 2008;8:45
• All: 1 reference(s)