Thap11^tm1Tpz
Targeted Allele Detail

Summary

• Symbol: Thap11^tm1Tpz
• Name: THAP domain containing 11; targeted mutation 1, Thomas P Zwaka
• MGI ID: MGI:3797582
• Synonyms: Ronin^flox
• Gene: Thap11 Location: Chr8:106581764-106583582 bp, + strand Genetic Position: Chr8, 53.05 cM, cytoband D2
• Alliance: Thap11^tm1Tpz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136306
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding region and an frt-flanked neo cassette with a 5' loxP site was inserted downstream of the coding region. (J:136306)

Expression

In Mice Carrying this Mutation:	26 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thap11 Mutation: 10 strains or lines available

References

• Original: J:136306 Dejosez M, et al., Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell. 2008 Jun 27;133(7):1162-74
• All: 4 reference(s)