Slc2a5^tm1.1Jnz
Targeted Allele Detail

Summary

• Symbol: Slc2a5^tm1.1Jnz
• Name: solute carrier family 2 (facilitated glucose transporter), member 5; targeted mutation 1.1, Jian Zuo
• MGI ID: MGI:3797586
• Synonyms: Glut5^-
• Gene: Slc2a5 Location: Chr4:150203801-150228625 bp, + strand Genetic Position: Chr4, 80.97 cM
• Alliance: Slc2a5^tm1.1Jnz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136820
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ line, cre-medited recombination was used to remove exons 1 through 4 and the neo cassette. The absence of protein product was confirmed by western blot analysis on testis extract. (J:136820)

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	Slc2a5^tm1.1Jnz/Slc2a5^tm1.1Jnz	involves: 129S6/SvEvTac * C57BL/6J * FVB/N

Phenotypes:

Affected Systems	hm1
show or hide all annotated terms
hearing/vestibular/ear	N
hearing/vestibular/ear phenotype	N

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a5 Mutation: 39 strains or lines available

References

• Original: J:136820 Wu X, et al., Glucose transporter 5 is undetectable in outer hair cells and does not contribute to cochlear amplification. Brain Res. 2008 May 19;1210:20-8
• All: 8 reference(s)