Unc93b1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Unc93b1^{tm1(KOMP)Vlcg}
• Name: unc-93 homolog B1, TLR signaling regulator; targeted mutation 1, Velocigene
• MGI ID: MGI:3797728
• Synonyms: Unc93b1^tm1Vlcg
• Gene: Unc93b1 Location: Chr19:3985222-3999340 bp, + strand Genetic Position: Chr19, 3.65 cM
• Alliance: Unc93b1^{tm1(KOMP)Vlcg} page
• IMPC: Unc93b1 gene page

Mutation origin

• Mutant Cell Lines: 10049A-B3, 10049A-B7, 10049A-C5, 10049A-F5, 10049A-G9, 10049A-G10
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 13703bp between positions 3985240-3998942 of Chromosome 19 (Build GRCm39). (J:136110)

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Unc93b1 Mutation: 39 strains or lines available

Notes

Cell line 10049A-G9 was successfully used to make chimeric mice. Germline transmission was accomplished. J: 211069

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 8 reference(s)