Tap1^rose
Chemically induced Allele Detail

Summary

• Symbol: Tap1^rose
• Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP); rose
• MGI ID: MGI:3797750
• Gene: Tap1 Location: Chr17:34406530-34416199 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Tap1^rose page

Mutation origin

• Strain of Origin: C57BL/6JApb
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation has been identified as an A-to-T transversion in exon 10 resulting in replacement of aspartic acid by valine at amino acid position 643 of the protein (D643V). (J:166104)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tap1 Mutation: 51 strains or lines available

References

• Original: J:166104 Theodoratos A, et al., Mouse strains with point mutations in TAP1 and TAP2. Immunol Cell Biol. 2010 Jan;88(1):72-8
• All: 1 reference(s)