Gria4^tm1Mony
Targeted Allele Detail

Summary

• Symbol: Gria4^tm1Mony
• Name: glutamate receptor, ionotropic, AMPA4 (alpha 4); targeted mutation 1, Hannah Monyer
• MGI ID: MGI:3798453
• Synonyms: GluA4fl, GluR-D^neo
• Gene: Gria4 Location: Chr9:4417896-4796234 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Gria4^tm1Mony page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136763
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 11 and an additional loxP site was inserted downstream of exon 11. (J:136763)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gria4 Mutation: 72 strains or lines available

References

• Original: J:136763 Fuchs EC, et al., Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron. 2007 Feb 15;53(4):591-604
• All: 8 reference(s)