Gria4^tm1.1Mony
Targeted Allele Detail

Summary

• Symbol: Gria4^tm1.1Mony
• Name: glutamate receptor, ionotropic, AMPA4 (alpha 4); targeted mutation 1.1, Hannah Monyer
• MGI ID: MGI:3798456
• Synonyms: GluR-D^-
• Gene: Gria4 Location: Chr9:4417896-4796234 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Gria4^tm1.1Mony page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136763
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ line, cre-mediated recombination was used to remove exon 11. The absence of transcript expression was confirmed by in situ hybridization of brain sections. (J:136763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gria4 Mutation: 72 strains or lines available

References

• Original: J:136763 Fuchs EC, et al., Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron. 2007 Feb 15;53(4):591-604
• All: 3 reference(s)