Hdgf^tm1Sefr
Targeted Allele Detail

Summary

• Symbol: Hdgf^tm1Sefr
• Name: heparin binding growth factor; targeted mutation 1, Sebastian Franken
• MGI ID: MGI:3798476
• Gene: Hdgf Location: Chr3:87813844-87823439 bp, + strand Genetic Position: Chr3, 38.78 cM
• Alliance: Hdgf^tm1Sefr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137170
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 6 were replaced with a GFP and HPRT cassette. The absence of protein product was confirmed by western blot analysis on total brain lysates. (J:137170)

Expression

In Mice Carrying this Mutation:

20 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdgf Mutation: 58 strains or lines available

References

• Original: J:137170 Gallitzendoerfer R, et al., Hepatoma-derived growth factor (HDGF) is dispensable for normal mouse development. Dev Dyn. 2008 Jul;237(7):1875-85
• All: 2 reference(s)