Slc18a3^tm1Mca
Targeted Allele Detail

Summary

• Symbol: Slc18a3^tm1Mca
• Name: solute carrier family 18 (vesicular monoamine), member 3; targeted mutation 1, Marc G Caron
• MGI ID: MGI:3798809
• Synonyms: VAChT^KD, VAChT KD^HOM
• Gene: Slc18a3 Location: Chr14:32184395-32186807 bp, - strand Genetic Position: Chr14, 19.4 cM
• Alliance: Slc18a3^tm1Mca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137284
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted into the coding region upstream of the translation intitiation codon. Reduced transcript production was confirmed by quantitative means. (J:137284)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc18a3 Mutation: 11 strains or lines available

References

• Original: J:137284 Prado VF, et al., Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 2006 Sep 7;51(5):601-12
• All: 17 reference(s)