Tcf4^tm1.1Hmb
Targeted Allele Detail

Summary

• Symbol: Tcf4^tm1.1Hmb
• Name: transcription factor 4; targeted mutation 1.1, Dan Holmberg
• MGI ID: MGI:3798811
• Synonyms: E2-2^-
• Gene: Tcf4 Location: Chr18:69476500-69821038 bp, + strand Genetic Position: Chr18, 43.23 cM, cytoband E2
• Alliance: Tcf4^tm1.1Hmb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136143
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ line, cre-mediated recombination was used to remove the exons encoding the bHLH and C-terminal domains. (J:65236)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf4 Mutation: 58 strains or lines available

References

• Original: J:136143 Wikstrom I, et al., A role for E2-2 at the DN3 stage of early thymopoiesis. Mol Immunol. 2008 Jun;45(11):3302-11
• All: 3 reference(s)