Mta2^tm1Yzha
Targeted Allele Detail

Summary

• Symbol: Mta2^tm1Yzha
• Name: metastasis-associated gene family, member 2; targeted mutation 1, Yi Zhang
• MGI ID: MGI:3798814
• Synonyms: Mta2^2lox
• Gene: Mta2 Location: Chr19:8919239-8929659 bp, + strand Genetic Position: Chr19, 6.04 cM, cytoband B
• Alliance: Mta2^tm1Yzha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137101
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A neo cassette with a 5' loxP site was inserted into intron 3 and an additional loxP site was inserted into exon 11. (J:137101)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mta2 Mutation: 38 strains or lines available

References

• Original: J:137101 Lu X, et al., Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. J Biol Chem. 2008 May 16;283(20):13825-33
• All: 2 reference(s)