Tg(Ggt1-cre/ERT2)1Pepe
Transgene Detail

Summary

• Symbol: Tg(Ggt1-cre/ERT2)1Pepe
• Name: transgene insertion 1, Petra Pennekamp
• MGI ID: MGI:3798834
• Synonyms: GGT:Cre-ER^T2, Tg(Ggt1-cre/ESR1)1Pepe
• Transgene: Tg(Ggt1-cre/ERT2)1Pepe Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Tg(Ggt1-cre/ERT2)1Pepe page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Ggt1-cre/ERT2)1Pepe expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ggt1 (MGI:95706)

• Mutation details: 411 bp of the mouse Ggt1 promoter was used to drive expression of an inducible cre/ERT2fusion in the proximal tubule of the kidney. One founder was created with 50 to 70 copies of the transgene integrated into the X chromosome. (J:137094)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ggt1 (mouse) Summary of all recombinase alleles driven by Ggt1. Comparative matrix view of recombinase activities Alliance mouse Ggt1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:137094 Dworniczak B, et al., Inducible Cre/loxP recombination in the mouse proximal tubule. Nephron Exp Nephrol. 2007;106(1):e11-20
• All: 4 reference(s)