Clca1^tm1Htzm
Targeted Allele Detail

Summary

• Symbol: Clca1^tm1Htzm
• Name: chloride channel accessory 1; targeted mutation 1, Michael Holtzman
• MGI ID: MGI:3799070
• Gene: Clca1 Location: Chr3:144710298-144738537 bp, - strand Genetic Position: Chr3, 69.26 cM
• Alliance: Clca1^tm1Htzm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137274
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A genomic fragment containing part of exon 7 through exon 11 was replaced with a neo cassette. (J:137274)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clca1 Mutation: 58 strains or lines available

References

• Original: J:137274 Patel AC, et al., Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members. Physiol Genomics. 2006 May 16;25(3):502-13
• All: 7 reference(s)