Syt10^tm1Sud
Targeted Allele Detail

Summary

• Symbol: Syt10^tm1Sud
• Name: synaptotagmin X; targeted mutation 1, Thomas C Sudhof
• MGI ID: MGI:3799077
• Gene: Syt10 Location: Chr15:89666596-89726063 bp, - strand Genetic Position: Chr15, 44.96 cM, cytoband F1
• Alliance: Syt10^tm1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137340
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The Syt 10 allele was created by inserting a tetracysteine tag (Flag-C(4)-Flag) in exon 2 of the gene. Exon 2 was additionally flanked by loxP sites. An Flp-neomycin-Flp cassette placed in intron 1 has been removed. (J:137340)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Syt10 Mutation: 35 strains or lines available

References

• Original: J:137340 Sudhof TC, Generation of a series of synaptotagmin mutant alleles. MGI Direct Data Submission. 2008
• All: 5 reference(s)