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Nup133Gt(RRK090)Byg
Gene trapped Allele Detail
Summary
Symbol: Nup133Gt(RRK090)Byg
Name: nucleoporin 133; gene trap RRK090, BayGenomics
MGI ID: MGI:3799269
Synonyms: Nup133GT
Gene: Nup133  Location: Chr8:124623862-124676004 bp, - strand  Genetic Position: Chr8, 72.27 cM
Alliance: Nup133Gt(RRK090)Byg page
Mutation
origin
Mutant Cell Line:  RRK090
Germline Transmission:  Earliest citation of germline transmission: J:137199
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT2Lxf     Vector Type: gene trap
 
Mutation detailsThe gene trap vector inserted into intron 5. Very low expression of the full length transcript was confirmed by western blot analysis on E9.5 whole embryo extracts. (J:137199)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 21 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nup133 Mutation:  58 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:137199 Lupu F, et al., Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo. Dev Cell. 2008 Jun;14(6):831-42
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory