Large1^myd-3J
Spontaneous Allele Detail

Summary

• Symbol: Large1^myd-3J
• Name: LARGE xylosyl- and glucuronyltransferase 1; myodystrophy 3 Jackson
• MGI ID: MGI:3799277
• Gene: Large1 Location: Chr8:73541227-74080164 bp, - strand Genetic Position: Chr8, 35.08 cM, cytoband C1
• Alliance: Large1^myd-3J page

Muscle degeneration in Large1^myd-3J/Large1^myd-3J mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: A noncomplementation test with the veils mutation demonstrated that this mutation is an allele of the Large gene.
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Large1 Mutation: 123 strains or lines available

References

• Original: J:160357 Curtain M, et al., A mouse mutation in the Large gene with muscular dystrophy and retinoschisis. MGI Direct Data Submission. 2010
• All: 1 reference(s)