Mavs^tm1Tsc
Targeted Allele Detail

Summary

• Symbol: Mavs^tm1Tsc
• Name: mitochondrial antiviral signaling protein; targeted mutation 1, Jurg Tschopp
• MGI ID: MGI:3799298
• Synonyms: Cardif^-
• Gene: Mavs Location: Chr2:131075983-131089945 bp, + strand Genetic Position: Chr2, 63.3 cM
• Alliance: Mavs^tm1Tsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136289
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2, containing the initiation methionine, through exon 5 were replaced with a neo cassette. (J:136289)

Expression

In Mice Carrying this Mutation:

24 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mavs Mutation: 36 strains or lines available

References

• Original: J:136289 Michallet MC, et al., TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity. 2008 May;28(5):651-61
• All: 31 reference(s)