Dync2h1^m152Asp
Chemically induced Allele Detail

Summary

• Symbol: Dync2h1^m152Asp
• Name: dynein cytoplasmic 2 heavy chain 1; mutation 152, Andrew S Peterson
• MGI ID: MGI:3799301
• Synonyms: Dnchc2^Q397Stop
• Gene: Dync2h1 Location: Chr9:6928550-7177619 bp, - strand Genetic Position: Chr9, Syntenic
• Alliance: Dync2h1^m152Asp page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: The molecular lesion is a C to A transversion in exon 8 that creates a stop codon at amino acid position 397 (Dnchc2Q397Stop). (J:103514)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dync2h1 Mutation: 215 strains or lines available

References

• Original: J:136795 Zarbalis K, et al., A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development. PLoS Biol. 2004 Aug;2(8):E219
• All: 2 reference(s)