Nedd4^tm1Bros
Targeted Allele Detail

Summary

• Symbol: Nedd4^tm1Bros
• Name: neural precursor cell expressed, developmentally down-regulated 4; targeted mutation 1, Nils Brose
• MGI ID: MGI:3799318
• Synonyms: Nedd4^-
• Gene: Nedd4 Location: Chr9:72569628-72657134 bp, + strand Genetic Position: Chr9, 40.08 cM
• Alliance: Nedd4^tm1Bros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137202
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Homologous recombination was used to remove exons 9 and 10. (J:137202)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nedd4 Mutation: 116 strains or lines available

References

• Original: J:137202 Fouladkou F, et al., The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8585-90
• All: 1 reference(s)