Apof^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Apof^{tm1(KOMP)Vlcg}
• Name: apolipoprotein F; targeted mutation 1, Velocigene
• MGI ID: MGI:3800154
• Synonyms: Apof^tm1Vlcg
• Gene: Apof Location: Chr10:128103866-128106022 bp, + strand Genetic Position: Chr10, 76.5 cM
• Alliance: Apof^{tm1(KOMP)Vlcg} page
• IMPC: Apof gene page

Mutation origin

• Mutant Cell Lines: 10417A-D6, 10417A-H2, 10417B-H8
• Germline Transmission: Earliest citation of germline transmission: J:185314
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1 Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1296bp between positions 127705793-127707088 of Chromosome 10 (Genome Build37). The cassette inserted into exon 1. RT-PCR confirmed the absence of transcript expression in the liver. (J:136110)

Generation of the Apof^tm1(KOMP)Vlcg allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Apof Mutation: 14 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)