Tg(IgkHyHEL10)1Rbr
Transgene Detail

Summary

• Symbol: Tg(IgkHyHEL10)1Rbr
• Name: transgene insertion 1, Robert Brink
• MGI ID: MGI:3800384
• Synonyms: LC2 Ig
• Transgene: Tg(IgkHyHEL10)1Rbr Location: unknown
• Alliance: Tg(IgkHyHEL10)1Rbr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IgkHyHEL10)1Rbr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igk (MGI:96494)

• Mutation details: The HyHEL10 hybridoma produces an antibody that binds hen egg lysozyme peptide (HEL) with high affinity . The transgenic construct contained the recombined gene segments of the HyHEL10 kappa light chain (Igk). Expression of the transgene was detected in B cells (J:132538)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available

References

• Original: J:132538 Phan TG, et al., B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J Exp Med. 2003 Apr 7;197(7):845-60
• All: 15 reference(s)