Tg(TcraDN32D3)#Alhn
Transgene Detail

Summary

• Symbol: Tg(TcraDN32D3)#Alhn
• Name: transgene insertion, Agnes Lehuen
• MGI ID: MGI:3800484
• Synonyms: Ja14-Ja18 TCR tg
• Transgene: Tg(TcraDN32D3)#Alhn Location: unknown
• Alliance: Tg(TcraDN32D3)#Alhn page

Transgene origin

• Strain of Origin: NOD

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TcraDN32D3)#Alhn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)

• Mutation details: The transgene contains the V-J exon from the rearranged Tcra gene of the C57BL/6-derived, CD1d1-reactive T cell hybridoma DN32D3; this cell line has the Tcra-V14-J281 rearrangement invariably borne by NK1 T lymphocytes. (J:93798)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:93798 Bendelac A, et al., Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells. J Exp Med. 1996 Oct 1;184(4):1285-93
• All: 20 reference(s)