Hydin^hyrh
Spontaneous Allele Detail

Summary

• Symbol: Hydin^hyrh
• Name: HYDIN, axonemal central pair apparatus protein; hydrocephalus with rhinitis
• MGI ID: MGI:3801608
• Gene: Hydin Location: Chr8:110993609-111336885 bp, + strand Genetic Position: Chr8, 57.5 cM
• Alliance: Hydin^hyrh page

Mutation origin

• Strain of Origin: B10.RIII-H2^r H2-T18^b/(71NS)SnJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This spontaneous C-to-T transition at position 110,575,054 (GRCm38) results in a change from arginine to a premature stop codon at residue 3806 (p.R3806*).
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hydin Mutation: 228 strains or lines available

References

• Original: J:137815 Dionne L, et al., A Hydrocephalus Mutation with Rhinitis on Mouse Chromosome Eight. MGI Direct Data Submission. 2008
• All: 2 reference(s)