Raver1^tm1Hha
Targeted Allele Detail

Summary

• Symbol: Raver1^tm1Hha
• Name: ribonucleoprotein, PTB-binding 1; targeted mutation 1, Hans-Henning Arnold
• MGI ID: MGI:3802576
• Gene: Raver1 Location: Chr9:20985454-21003295 bp, - strand Genetic Position: Chr9, 7.71 cM, cytoband A3
• Alliance: Raver1^tm1Hha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137591
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 through 3 were replaced with a lacZ gene and a floxed neo cassette. Germ line, cre-mediated recombination was used to remove the neo cassette. The absence of protein product was confirmed by western blot analysis on muscle, heart, intestine and brain extracts. (J:137591)

Expression

In Mice Carrying this Mutation:

52 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Raver1 Mutation: 22 strains or lines available

References

• Original: J:137591 Lahmann I, et al., The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity. Exp Cell Res. 2008 Mar 10;314(5):1048-60
• All: 1 reference(s)