Igkc^tm1Jkbv
Targeted Allele Detail

Summary

• Symbol: Igkc^tm1Jkbv
• Name: immunoglobulin kappa constant; targeted mutation 1, Aya Jakobovits
• MGI ID: MGI:3802625
• Synonyms: deltaCkappa
• Gene: Igkc Location: Chr6:70703419-70703738 bp, + strand Genetic Position: Chr6, 32.04 cM, cytoband C
• Alliance: Igkc^tm1Jkbv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:23827
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The Ckappa region was deleted to inactivate the mouse Igkappa locus. (J:23827)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igkc Mutation: 9 strains or lines available

References

• Original: J:23827 Green LL, et al., Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat Genet. 1994 May;7(1):13-21
• All: 7 reference(s)